Mental Health
Biophysicists long for an ideal material - something more structured and less sticky than a standard glass surface - to anchor and position individual biomolecules. Gold is an alluring possibility, with its simple chemistry and the ease with which it can be patterned. Unfortunately, gold also tends to be sticky and can be melted by lasers. Now, biophysicists at JILA have made gold more precious than ever - at least as a research tool - by creating nonstick gold surfaces and laser-safe gold nanoposts, a potential boon to laser trapping of biomolecules.
It is known that more intensive management of hypertension can improve blood pressure control and thus improve cardiovascular outcomes. However, there are several different systems of measuring the intensity of management of hypertension, and they have not been previously compared. If one system performs best, it would be important to use it to measure intensity of management for research and quality improvement purposes. Researchers from Boston University have compared different measures of treatment intensity in hypertension care and have found that one of the measures should be preferred to the others. This study, which appears in the July issue of Circulation: Cardiovascular Quality and Outcomes, shows that the measure originally described by Okonofua, et al. (Hypertension, 2006) predicts blood pressure control more effectively than the other two measures studied.
UBC researchers have created the world"s first animal laboratory experiment to successfully model human gambling. The advance will help scientists develop and test new treatments for gambling addictions, a devastating condition that affects millions worldwide.
The results of an international study led by a Toronto-area doctor were unveiled today that show there"s a more effective way to treat patients with a severe arrhythmia, or irregular heartbeat, than the current treatment methods.
A polyomavirus known as MCPyV is associated with clinical outcomes, including fewer metastases and better survival, in patients with a rare form of skin cancer called Merkel cell carcinoma, according to a new study published online June 17 in the JNCI.
The American Society of Interventional Pain Physicians (ASIPP) announced that the National All Schedules Prescription Electronic Reporting (NASPER) Act has received the support of Senator John D. Rockefeller IV of West Virginia and Senator Bob Corker of Tennessee.
Provectus Pharmaceuticals, Inc. (OTC BB: PVCT), a development-stage oncology and dermatology biopharmaceutical company has completed patient accrual and initial PV-10 treatment in its Phase 2 trial of PV-10 for metastatic melanoma. The study involved treatment of 80 subjects with Stage III or Stage IV metastatic melanoma.
Doctors in the Netherlands have developed new ways to perform radiosurgery on benign acoustic tumors using fast and precise RapidArc(TM) radiotherapy technology from Varian Medical Systems (NYSE: VAR). This is among the findings in several papers published by the team at VU University Medical Center in Amsterdam.
Omega-3 fatty acids found in fatty fish such as tuna and salmon may protect against progression of age-related macular degeneration (AMD), but the benefits appear to depend on the stage of disease and whether certain supplements are taken, report researchers at the Laboratory for Nutrition and Vision Research (LNVR), Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University.
Thousands of unregistered Rohingya refugees living in the Kutupalong makeshift camp, Bangladesh, are being forcibly displaced from their homes, in an act of intimidation and abuse by the local authorities. The international medical organization Doctors Without Border/Mç©decins Sans Frontiç¨res (MSF) has treated numerous people for injuries, of which the majority were women and children. Furthermore, MSF has witnessed countless destroyed homes and heard many reports of people being warned to remove their own shelters or face the consequences.
The Honourable Leona Aglukkaq, Minister of Health, and Dr. Chen Zhu, Minister of Health for the People"s Republic of China, today signed a Plan of Action for continued cooperation between the two countries on health priorities of mutual concern. The signing ceremony followed discussions among senior Canadian and Chinese health officials and experts on a range of health issues, including strengthening and reform of health-care systems, primary health care and food safety.
The Wall Street Journal/Dow Jones Newswires reports on reaction to the Obama administration"s proposed cuts that may acutely affect hospitals. It notes: "President Obama last weekend called for $313 billion in savings over 10 years through adjustments in Medicare and Medicaid payments - a plan that a "deeply disappointed" American Hospital Association said would mean $220 billion in payment cuts to hospitals, on top of billions in other proposed Medicare cuts."
Newspapers highlight a few of the key congressional players in the health care debate.
Scientists at Johns Hopkins have discovered a potential strategy for cancer therapy by focusing on what"s missing in tumors.
Paul Thorn - project director of the Tuberculosis Survival Project, who was scheduled to speak at the Pacific Health Summit in Seattle on Wednesday - has called on the Obama administration to change the policy banning people who are HIV-positive from entering the U.S., the Seattle Times" blog, the "Business of Giving," reports. Thorn said he was denied a U.S. visa because he is HIV-positive and issued an apology to summit attendees for his absence, which stated, "The U.S. government actively discriminates against people" who are HIV-positive adding that if U.S. officials want to demonstrate leadership on HIV/AIDS and global health by hosting such conferences, "then they need to accept that non-U.S. citizens with HIV are going to need to be there and participate." One of the key topics for the conference is HIV and tuberculosis coinfection (Heim, "Business of Giving"/Seattle Times, 6/17).
A Delaware-based organization that has provided HIV prevention, outreach, education and other services for the past 28 years will be closing due to lack of funding, the Bethany Beach Wave reports. The Sussex County AIDS Committee (SCAC) also provided financial assistance, transportation services and assistance with medical appointments to people living with HIV/AIDS from as far as Philadelphia, according to the Wave. SCAC was funded by both private and government funding. "We just ran out of money," Curt Barrows, president of the SCAC board, said. CAMP Rehoboth, another local organization, said it will step in to assist SCAC clients (Shockley, Bethany Beach Wave, 6/18).
The Guardian examines the recent U.S. commitment to continue support for the development of Nigeria"s health and education sector by Anne Fleuret, Nigeria"s acting mission director of USAID. At the conclusion of two USAID-funded projects in Nigeria, Fleuret said the HIV/AIDS programs were created six years ago "to empower communities." She added, "We envisioned so many things and we have substantially achieved that vision. We have provided support from the community level to the legislative level."
President Obama last week disbanded the Bush administration"s Council on Bioethics and announced plans to form a new commission with a mandate that will offer "practical policy options," according to White House press officer Reid Cherlin, the New York Times reports. According to Cherlin, the old council was disbanded because former President George W. Bush"s administration designed it to be "a philosophically leaning advisory group" that focused on discussion rather than forming a shared consensus. Presidential bioethics commissions, which have existed since 1974, typically serve to inform the public of advances in science and develop guidance on controversial issues such as stem cells, human cloning and genetic engineering, the Times reports.The Bush administration"s council was created in November 2001, shortly after Bush restricted federal funding for embryonic stem cell research to lines existing at the time. Bush"s council at times was accused of being more ideological than previous commissions, particularly under the leadership of Leon Kass of the University of Chicago, the Times reports. It often produced reports with "a somewhat philosophical bent" on issues like how to determine death or the genetic screening of newborns, according to the Times. Alta Charo, an ethicist at the University of Wisconsin, said much of the council"s work "seemed more like a public debating society." Ruth Faden, a bioethicist at Johns Hopkins University, said, "The other view is that all presidential commissions are structured in the context of a particular administration" (Wade, New York Times, 6/18).
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Scientists have unearthed striking evidence for a sudden ancient collapse in plant biodiversity. A trove of 200 million-year-old fossil leaves collected in East Greenland tells the story, carrying its message across time to us today.
Under legislation reported by the Senate Committee on Small Business and Entrepreneurship, small companies that receive the majority of their financing from venture capital will once again be considered eligible to compete for Small Business Innovation Research (SBIR) grants. The change will allow more small biotechnology start-ups to compete for these funds and continue critical research and development of medical advancements and breakthroughs. Biotechnology Industry Organization (BIO) President and CEO Jim Greenwood made the following statement today:
Power of the Dream Ventures, Inc. (OTCBB: PWRV), Hungary"s premier technology acquisition and development company, is pleased to present this Genetic Immunity release, based on a previously announced agreement whereby Power of the Dream Ventures will issue communications for Genetic Immunity on an ongoing basis.
A period, or menstruation, is the shedding of the endometrium - the uterine lining. Menstruation is also known as menses. All female humans, as well as some other female mammals, have regular periods during their reproductive age. Menstruation which includes bleeding from the vagina is found mainly among humans and similar animals, such as primates. In many mammals, the endometrium is reabsorbed by the animal. As far as humans are concerned a period is a bleed from the womb (uterus) that is released through the vagina. Women have a period every 28 days approximately. However, some women may have a 24-day cycle while other may have a 35-day one. A period is part of the woman"s menstrual cycle.
Accuray Incorporated (Nasdaq: ARAY), a global leader in the field of radiosurgery, announced that the Turkish Ministry of Health has purchased two CyberKnife(R) Robotic Radiosurgery Systems for installation in Ankara and Istanbul, Turkey.
German children are taller than 30 years ago, but the increase in height observed during the last century has become slower. In the current edition of Deutsches Arzteblatt International (Dtsch Arztebl Int 2009; 106(23): 377-82), Bettina Gohlke and Joachim Woelfle of the Department of Pediatrics at the University of Bonn summarize the current state of knowledge of changes in height and of the physical development of young people.
The American Lung Association released its State of the Air: 2009 Report this month. The 10th annual report states that air pollution has significantly improved in some areas of the country, but major cities still have significant problems with pollutants.
Most people have experienced the odd sleepless night before a crucial exam, a job interview or before going on holiday, but few people get by with just a couple of hours of sleep a day, every day.
The European Medicines Agency is inviting comments on its draft
World hunger is projected to reach a historic high in 2009 with 1 020 million people going hungry every day, according to new estimates published by FAO today.
Indiana University School of Medicine researchers have developed a new breast cancer diagnostic marker that could enable physicians to more easily determine which patients have a less aggressive form of the disease that may not require chemotherapy treatment.
Canada and the United States have reached an agreement that will give organic producers access to more markets and make sure Canadian families can find more organic products in their grocery stores.
Food supplementation programs for women, infants and children are among the strategies that should be trialled to improve nutrition in Indigenous communities, according to an editorial published in the May 18 Indigenous Health issue of the Medical Journal of Australia.
"The high cost of securing health insurance for all Americans, the top domestic priority of President Obama, has Congressional Democrats scrambling to scale back their proposals or find ways to trim tens of billions of dollars a year from existing health programs," the New York Times reports. Early estimates for the cost of the Senate Finance Committee"s reform proposal are far higher than anticipated, forcing leading senators in charge of shaping the legislation into a holding pattern as they seek lower-cost alternatives. Among the items being considered: ""an automatic mechanism" to reduce the growth of Medicare under an expedited procedure like the one used to close military bases" and a requirement that some employers contribute to the cost of Medicaid or private health insurance for low-wage workers.
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Outpatient clinics in District General Hospitals operating on a weekly basis are not able to reach minimum standards for treating patients who have suffered a stroke, according to a new audit published by the Royal College of Physicians. The study, published in Clinical Medicine journal, assessed the timeliness with which an urgent access neurovascular clinic was able to evaluate possible stroke victims between 2000 and 2006. Data showed that the clinic was not able to reach the National Clinical Guideline for Stroke"s recommendation that patients who may have suffered a minor stroke or transient ischaemic attack (TIA) receive urgent evaluation within one week.
CNN examines race disparities in health care during a 4-minute segment that is part of the station"s week-long focus on health care issues.
The U.S. Food and Drug Administration and the Centers for Disease Control and Prevention are warning consumers not to eat any varieties of prepackaged Nestle Toll House refrigerated cookie dough due to the risk of contamination with E. coli O157:H7 (a bacterium that causes food borne illness).
This data shows the NHS" progress in tackling the waiting times for
BBC examines a campaign in sub-Saharan Africa that is helping to distribute drugs to prevent onchocerciasis, also known as river blindness - a disease "caused by a parasite that is spread from human to human by the black fly, which once flourished along river beds where there is fast-flowing water." According to the BBC, "Some 35 million people are currently infected with river blindness, and about 140 million people in Africa are at risk of infection."
The following summarizes selected women"s health-related blog entries.~ "A Radical Notion: Women"s Health Care as Mainstream," Cecile Richards, Huffington Post blogs: "To hammer ... home" the message that "Planned Parenthood and other essential community providers are the affordable, local access to basic preventive care that saves lives," the Planned Parenthood Action Center has introduced advertisements "educating the policy folks involved in fixing our health care system" about "why women"s health care needs to be taken care of in this mega-reform effort," Richards writes. She writes, "From cancer screenings to contraception to immunizations, the majority of women who go to women"s health care centers consider them their primary health care provider," adding, "In fact, more than 90% of what Planned Parenthood health centers do is preventive and primary care." According to Richards, "Essential community providers, including those who provide women"s health care, need to be part of any newly established health care system." She adds that "the three million patients who came to Planned Parenthood health centers last year can testify to it." Richards writes that "[f]amily planning and reproductive health care are unfortunately still not fully part of mainstream health care, even though 98% of women use contraception at some point in their lives -- there"s nothing more universal!" The "fact that women reproduce and, therefore, have different types of health care needs makes some folks on Capitol Hill go pale and start to sweat," Richards writes. She concludes, "Maybe one day we won"t need a special campaign to support women"s health," but "until then, Planned Parenthood is here to make sure women aren"t worse off after health care reform than before" (Richards, Huffington Post blogs, 6/18).~ "The Role of Medical Education in Preserving Abortion Access," Our Bodies, Our Blog: In response to a recent Salon opinion piece that examined whether there will be a next generation of abortion providers, the blog post discusses a few organizations that are "working to increase access to (accurate) abortion-related training." The blog includes links to Medical Students for Choice -- a group that "does student organizing and advocacy to influence medical school curricula, workshops ... and lectures on abortion techniques" -- and The Ryan Program -- which offers "funding, technical expertise, curriculum, workshops and other res to support training opportunities in abortion and contraception for ob-gyn residents." The blog entry also highlights the work of Physicians for Reproductive Choice and Health, which partners with members of the American Medical Student Association "to provide "project in a box" materials for medical students wanting to access and influence their schools" curricula on sexual and reproductive health" (Our Bodies, Our Blog, 6/18). ~ "Regulating Abortion May Be OK But Not To Avoid Sex-Selection," Marianne Mollmann, Huffington Post blogs: "Sex-selective abortion raises a multitude of overlapping ethical concerns regarding eugenics, population control and provider privilege or knowledge," according to Mollmann, advocacy director for the Human Rights Watch"s Women"s Rights Division. Mollmann writes that recent media reports indicating that sex-selective abortion occurs among some ethnic communities in the U.S. "has generated new discussion about what to do -- indeed what to think -- about the practice here." She continues that the "effect of abortion regulations depends on the context and motivation," adding that "[f]rom a human rights perspective, the regulation of medical procedures and interventions is legitimate and indeed often necessary so long as they are based on full respect for the full range of human rights." It is "perhaps tempting to hope that banning sex-selective abortions would safeguard the gender balance of future generations," but the "criminalization of abortion for whatever reason has in the past led only to underground and unsafe prac
Eli Lilly and Company presented data on the short- and long-term efficacy and safety of olanzapine long-acting injection (LAI) in the treatment of adults with schizophrenia or schizoaffective disorder. Olanzapine LAI is an investigational formulation that combines the atypical antipsychotic Zyprexa(R) (olanzapine) with pamoic acid, allowing for the sustained delivery of olanzapine for up to four weeks.
Obesity is probably the most important factor in the development of insulin resistance, but science"s understanding of the chain of events is still spotty. Now, researchers at the Salk Institute for Biological Studies have filled in the gap and identified the missing link between the two. Their findings, to be published in the June 21, 2009 advance online edition of the journal Nature, explain how obesity sets the stage for diabetes and why thin people can become insulin-resistant.
Notch signaling helps determine the fate of a number of different cell types in a variety of organisms, including humans. In an article that appears in the current issue of Nature Cell Biology, researchers at Baylor College of Medicine report that a new finding about the Notch signaling pathway in sensory organ precursor cells in the fruit fly could explain the mystery behind an immunological disorder called Wiskott-Aldrich syndrome.
"Moving to a more continuous follow-up approach would have the tremendous advantages of enhancing patient safety, decreasing physician and nurse work load, and allowing health staff to focus on medical emergencies," urged Professor Angelo Auricchio, from the European Heart Rhythm Association (EHRA) and official spokesperson of the European Society of Cardiology (ESC), adding that such systems may have the additional advantage of being more cost effective for health care providers.
With rising taxes and increasing restrictions on smoking and tobacco, smokers looking for temporary relief from cravings and withdrawal symptoms during periods when they couldn"t smoke, or chose not to, were out of luck. But a new breed of short-term cessation treatment -- based on age-old homeopathic practices -- promises to help smokers manage cravings on-the-spot, when lighting up isn"t an option.
The fulfilment which so many people increasingly derive from competitive sports and endurance training comes with a real - even if rare - twist. Because, while most people will enjoy the benefits and pleasures of exercise, there are a few for whom regular athletic training will increase the risk of cardiac arrhythmias and even sudden death, especially among those in middle-age or with pre-existing cardiac diseases.
Merck & Co., Inc. said it supports a proposal to provide additional assistance to Medicare Part D beneficiaries who have reached the coverage gap (donut hole) in their prescription benefit.
"There are data in the literature suggesting an increased mortality in patients with chronic heart failure who are additionally suffering from cognitive decline", said Dr. Clotilde Balucani (Perugia, Italy) at the current meeting of the European Neurological Society (ENS). This major meeting in European neurology is gathering more than 2,900 experts from all over the world in Milan. Dr. Balucani and her colleagues are presenting a study funded by a research grant of the ENS.
Ca2+/calmodulin-dependent protein kinase II alpha (CaMKII alpha) is an enzyme that adds phosphates to a variety of protein substrates to modify their functions. CaMKII alpha is enriched in the hippocampus, the memory center of the brain, and is believed to be an essential mediator of activity-dependent synaptic plasticity and memory functions. However, the causative role of the enzymatic activity of CaMKII alpha in such processes has not been demonstrated yet, because this enzyme has multiple protein functions other than the kinase activity. A Japanese research group, led by Dr Yoko Yamagata of the National Institute for Physiological Sciences, Japan, has successfully generated a novel kinase-dead mutant mouse of the CaMKII alpha gene that completely and exclusively lacks its kinase activity. They examined hippocampal synaptic plasticity and behavioral learning of the mouse, and found a severe deficit in both processes. They reported their findings in the Journal of Neuroscience, published on June 10, 2009.
The goal of creating adult blood stem cells from human embryos to prepare a patient for tissue and organ transplant has been brought a step closer by research carried out at the MRC Molecular Haematology Unit at Oxford University.
The Ministry of Health in Iran has reported the country"s first confirmed case of H1N1 swine flu, in a 16 year-old Iranian boy who lives in the US
A PET scan uses radiation, or nuclear medicine imaging, to produce 3-dimensional, color images of the functional processes within the human body. PET stands for positron emission tomography. The machine detects pairs of gamma rays which are emitted indirectly by a tracer (positron-emitting radionuclide) which is placed in the body on a biologically active molecule. The images are reconstructed by computer analysis. Modern machines often use a CT X-ray scan which is performed on the patient at the same time in the same machine.
As the weather gets warmer, people often get motivated to spend more time outdoors. Whether it"s working on projects around the house, playing with the grandkids at the park or out exercising, the American Academy of Orthopaedic Surgeons (AAOS) stresses important that baby boomers remember their bodies are not as young as they used to be and not overdo it.
South Dakota State University research shows that a child with leaner body mass, or muscle, builds bigger bones than a child who weighs the same but has a greater percentage of fat.
A research team may have broken the stubborn impasse that has frustrated the invention of an effective HIV vaccine, by using an approach that bypasses the usual path followed by vaccine developers. By using gene transfer technology that produces molecules that block infection, the scientists protected monkeys from infection by a virus closely related to HIV -- the simian immunodeficiency virus, or SIV -- that causes AIDS in rhesus monkeys.
The American College of Obstetricians and Gynecologists (ACOG) has launched a new website devoted to women who are approaching or going through menopause to provide them with the necessary information they need to make informed decisions about their health. The ACOG-sponsored website can be found at http://pause.acog.org.
Janssen(R), Division of Ortho-McNeil-Janssen Pharmaceuticals, Inc. announced the U.S. Food and Drug Administration (FDA) has approved the Supplemental New Drug Applications (sNDAs) for the use of RISPERDAL(R) CONSTA(R) (risperidone) Long-Acting Treatment as both monotherapy and adjunctive therapy to lithium or valproate in the maintenance treatment of Bipolar I Disorder.
The National Minority Quality Forum (NMQF) today launched an online tool that maps the prevalence of HIV and AIDS by county, age, gender and ethnicity in all 50 states, Washington, D.C., Puerto Rico and the U.S. Virgin Islands, the San Francisco Chronicle reports. The HIV/AIDS Atlas is based on 2006 data collected from states and cross-checked with CDC data. The NMQF partnered with George Washington University"s School of Public Health and Health Services to collect and analyze the data. Gary Puckrein, chief executive officer of NMQF, said the new tool will help improve data collection and analysis, prevention initiatives, early diagnosis and routine testing efforts in areas most affected by HIV/AIDS (Colliver, San Francisco Chronicle, 6/21).
The Senate on Friday confirmed President Obama"s U.S. Global AIDS Coordinator nominee Eric Goosby, the San Francisco Chronicle reports. Goosby - who "served previously in the Clinton administration as director of HIV/AIDS policy in the Department of Health and Human Services and as chief adviser to the president on HIV-related issues" - will now "head the U.S. strategy for addressing HIV around the world, and oversee the implementation of the President"s Emergency Plan for AIDS Relief" (PEPFAR), the newspaper writes. Goosby "has more than 25 years of experience treating HIV/AIDS," and most recently served as chief executive officer and chief medical officer of the Pangaea Global AIDS Foundation, which is affiliated with the San Francisco AIDS Foundation, according to the San Francisco Chronicle (Doyle, San Francisco Chronicle, 6/20).
The National Organization for Women on Saturday during its annual conference elected Terry O"Neill as the group"s new president, the Indianapolis Star reports. O"Neill succeeds Kim Gandy, who has served two four-year terms as NOW president. The group has grown to include about 500,000 advocate members since its founding in 1966.During the conference, participants discussed a number of women"s rights issues, including same-sex marriage, equal pay and health insurance affordability. O"Neill raised the issue of "conscience" clauses, which allow health care workers to refuse to provide information or services on moral or religious grounds. O"Neill said, "Conscience clauses, where pharmacists refuse birth control sales because it"s against their conscience, must go. Guess what? Women have a constitutional right to birth control," adding, "There is no constitutional right to be a pharmacist" (Jacobs, Indianapolis Star, 6/21).O"Neill served as NOW"s vice president for membership from 2001 to 2005. She most recently served as chief of staff for a county council member in Montgomery County, Md. O"Neill in a prepared statement said that she is "honored and eager" to lead NOW (AP/Google.com, 6/21).
MMR Information Systems, Inc. (OTCBB: MMRF) (the "Company"), which through its wholly-owned operating subsidiary, MyMedicalRecords, Inc. ("MMR") provides consumer-controlled Personal Health Records ("PHRs") (http://www.mymedicalrecords.com) and electronic safe deposit box storage solutions (http://www.myesafedepositbox.com), announced that it has taken the necessary steps to file for extensions of the Company"s Patent Cooperation Treaty (PCT) patent application on anti-CD20 monoclonal antibodies to the national phase through filings in major European, Asian, North American, and South American markets.
The natriuretic peptide (NP) receptor type B (NPR-B) gene was expressed in gastric smooth muscles of normal and diabetic rats and the expression was increased in diabetic rats. These results suggest that natriuretic peptide-dependent pGC-cGMP signal is up-regulated and it may contribute to diabetic gastroparesis in STZ-induced diabetic rat.
Appendicitis is the most common childhood surgical emergency, but the diagnosis can be challenging, especially in children, often leading to either unnecessary surgery in children without appendicitis, or a ruptured appendix and serious complications when the condition is missed. Now, emergency medicine physicians and scientists at the Proteomics Center at Children"s Hospital Boston demonstrate that a protein detectable in urine might serve as a "biomarker" for appendicitis. Their report was published online June 23 by the Annals of Emergency Medicine.
Enzon Pharmaceuticals, Inc. (Nasdaq: ENZN) announced that it has opened its first Phase II trial for PEG-SN38 (EZN-2208), its novel proprietary cancer compound. The trial is open at multiple centers throughout the United States for patients diagnosed with metastatic colon cancer.
BloodCenter of Wisconsin"s Diagnostic Laboratories announced that it is the first laboratory in the United States to develop and offer a genetic test, known as "CEBPA Mutation Analysis," for inherited acute myeloid leukemia (AML). AML is the second most common form of leukemia.
U-Systems, the leader in dedicated breast ultrasound systems, together with Medical Director Jessica A. Guingrich, MD of OSF Saint Francis Medical Center, Susan G. Komen Breast Center and Centers for Breast Health announced that they have initiated the SOMOò€¢INSIGHT Clinical Study. The first participants have been enrolled and the first pathologically confirmed cancer has been detected in a mammographically-negative screening patient. The clinical study is examining whether Digital Mammography along with the somoò€¢v™ Automated Breast Ultrasound (ABUS) is more sensitive to detecting breast lesions when compared to Mammography alone in women with dense breasts.
A tiny plant with a long name (Arabidopsis thaliana) helps researchers from over 120 countries learn how to design new crops to help meet increasing demands for food, biofuels, industrial materials, and new medicines. The genes, proteins, and other traits of this fast-growing, tiny mustard plant reside in a vast database dubbed the Arabidopsis Information Re (TAIR), which has over 1.6 million page hits each month. The TAIR group, headed by Dr. Eva Huala at Carnegie"s Department of Plant Biology, just released a new version of the genome sequence of this model plant, which includes an array of improvements and novel features that promise to accelerate this critical research.
Pre-hospital emergency care in the form of
A faculty member of the Department of Sociology and Anthropology at the University of Haifa presented the results of a new research at an international Holocaust conference held at the University of Haifa.
The nation"s drugmakers have pledged tens of billions of dollars to reduce seniors" out of pocket Medicare Part D drug costs, President Barack Obama announced today. In response, National Community Pharmacists Association (NCPA) Executive Vice President and CEO Bruce T. Roberts, RPh, issued the following statement:
Greater influence over everyday life, emotional support, and cultural and recreational activities help to enable teenage girls to withstand stress. Those were the results of a dissertation from the Sahlgrenska Academy, University of Gothenburg, Sweden.
We humans prefer to be addressed in our right ear and are more likely to perform a task when we receive the request in our right ear rather than our left. In a series of three studies, looking at ear preference in communication between humans, Dr. Luca Tommasi and Daniele Marzoli from the University "Gabriele d"Annunzio" in Chieti, Italy, show that a natural side bias, depending on hemispheric asymmetry in the brain, manifests itself in everyday human behavior. Their findings were just published online in Springer"s journal Naturwissenschaften.
A group of German investigators demonstrated that the early increase in phosphorylated CREB (pCREB) is related to treatment response and does not depend on pharmacological interventions or brain-derived neurotrophic factor (BDNF) plasma levels. For the first time, cellular biological markers could be associated with response to psychotherapy.
A team of scientists led by chemist and NWO Pioneer laureate Piet Gros and medical microbiologist Jos van Strijp from Utrecht University have succeeded in freezing a chain reaction of the immune system. This achievement marks a breakthrough in the field of immunology. The researchers from Utrecht University, University Medical Centre Utrecht and the University of Pennsylvania, published their findings on 7 June with two simultaneous articles in Nature Immunology.
The Employment Policies Institute (EPI) released a new study which shows that the widely employed estimate of 47 million uninsured Americans is a misleading representation of the problem. The study, authored by Drs. June and David O"Neill of Baruch College and City University of New York, shows that more than 43 percent, or 18 million, of uninsured Americans ages 18-64 could likely afford health coverage and are actually "voluntarily uninsured." June O"Neill served as Director of the Congressional Budget Office (CBO) from 1995-1999.
The American Pain Society (APS) has issued a new clinical practice guideline for low back pain that emphasizes the use of noninvasive treatments over interventional procedures, as well as shared decision making between provider and patient. The findings are published in the current (May 1, 2009) issue of the journal Spine.
While suffering a major stroke at her home near Mena, Iva Sikes assumed the worst, not knowing that a University of Arkansas for Medical Sciences (UAMS)-led telemedicine program would provide her a complete recovery.
An article published Online First and in the July edition of The Lancet Oncology indicates that weight-loss surgery known as bariatric surgery could be linked to a reduction in cancer risk in obese women, but not in obese men.
A study that attempted to replicate the "seminal" study that laid the
Today the House Energy and Commerce Committee"s subcommittee on Health began what will be week-long hearings on a draft of the Democrats" health care reform plan. Congressman Michael C. Burgess, M.D. (R-Texas), a member of the Health subcommittee, said he looks forward to learning more about the draft plan, but believes the hearings are a far-cry from real bipartisan efforts.
More than 500 scientific abstracts to be presented across 20 types of
The New Mexico Department of Health announced today that a 65-year-old man from San Miguel County is hospitalized in critical condition at University of New Mexico Hospital in Albuquerque with the state"s second case of Hantavirus Pulmonary Syndrome this year. The Department of Health confirmed the case of Hantavirus on Wednesday and is conducting an environmental investigation to look for places where the man may have been exposed to the virus.
The Mississippi State Department of Health (MSDH) reports 22 new cases of H1N1 swine flu for last week, bringing the state"s total number of cases to 105. The new cases last week were in Lamar (6), Rankin (4), Covington (2), Madison (2), Chickasaw (1), Forrest (1), Harrison (1), Jackson (1), Lafayette (1), Monroe (1), Warren (1) and Winston (1) counties.
The Rhode Island Department of Health (HEALTH) recognizes and applauds the significant public health achievement of The Family Smoking Prevention and Tobacco Control Act being signed into law. This new law gives the U.S. Food and Drug Administration (FDA) the authority to regulate tobacco products.
CNN looks at the lives of teenagers and young adults who were born with HIV before advancements in antiretroviral drugs in the 1990s helped prevent mother-to-child transmission. According to CNN, these children "have defied initial expectations" and "danced at their high school proms, walked on stage to receive their diplomas and even experienced the birth of their children." The article profiles a group of HIV-positive teenagers and young adults in Miami called the Kool Kids. The group was established in 1995 to help children living with HIV cope with the "usual complications of adolescence" and also the "broken families, medical complications and fights for acceptance" that exist as a result of their HIV (Park, CNN, 6/22).
The Maine Center for Disease Control and Prevention of the Maine Department of Health and Human Services, is issuing an advisory about the danger of carbon monoxide poisoning when people open camps for the summer.
Researchers at the University of Texas Medical Branch at Galveston have discovered two biochemical pathways that the Ebola virus relies on to infect cells. Using substances that block the activation of those pathways, they"ve prevented Ebola infection in cell culture experiments - potentially providing a critical early step in developing the first successful therapy for the deadly virus.
New research from Vanderbilt University indicates the way our brain handles how we move through space - including being able to imagine literally stepping into someone else"s shoes - may be related to how and why we experience empathy toward others.
This is one of the findings of Sophia Shaw and colleagues from the University of Leicester who will present their research at the British Psychological Society Division of Forensic Psychology Annual Conference today, Tuesday 23rd June, at the University of Central Lancashire, Preston.
Research presented by Bernard Casey of the University of Warwick"s Institute for Employment Research shows that work-related stress today damages national output even more than the loss to national output due to strikes at the peak of industrial unrest in the 1970s.
Researchers at the Universities of Leeds and Bristol (UK) have developed a model of how errors are corrected whilst proteins are being built.
Multiple sclerosis, diabetic neuropathy, and other conditions caused by a loss of myelin insulation around nerves can be debilitating and even deadly, but adequate treatments do not yet exist. That"s in large part because of deficiencies in model research systems. In an upcoming issue of the journal Biomaterials, a UCF team addresses this problem with a report on the first lab-grown motor nerves that are insulated and organized the same way they are in the body. The group"s model system, along with further advances now within reach, could dramatically improve understanding of the causes of myelin-related conditions, and enable discovery and testing of new drug therapies.
Kamalesh Sirkar, PhD, distinguished professor of chemical engineering at NJIT, and internationally-renowned expert in membrane separation technologies will be the recipient of the NJIT Board of Overseers Excellence in Research Prize and Medal. The award presentation and lecture will take place Wednesday, Oct. 7, 2009, in Kupfrian Hall on the NJIT campus.
Living Cell Technologies Limited (ASX: LCT; OTCQX: LVCLY) announced that the New Zealand Minister of Health, the Honourable Tony Ryall, has authorized LCT"s New Zealand Phase I/IIa clinical trial of DIABECELL(R) for insulin dependent diabetes.
Novasys Medical, Inc., a developer of innovative therapies in women"s health, announced that as of July 1, 2009, First Coast Service Options, Inc. ("First Coast"), a large regional Medicare carrier serving over 3 million beneficiaries in Florida, Puerto Rico and the U.S. Virgin Islands, has removed the non-surgical Renessa(R) treatment for women with stress urinary incontinence (SUI) from its noncovered services list and will be looking at claims for the Renessa procedure on an individual case by case basis.
A group led by Columbia University Medical Center"s Timothy Wang, M.D., has studied the role of Helicobacter infection in the development of stomach cancer and found that the hormone gastrin, which stimulates secretion of gastric acid, plays a key role in the development of Helicobacter-induced stomach cancer, and may have distinct effects on carcinogenesis in different parts of the stomach.
From the west to east coast, Americans are experiencing record-breaking temperatures. Some states are reporting triple-digit numbers and the heat has been the cause of several reported deaths. "Children and the elderly are considered the most vulnerable population. It is harder for their bodies to respond to these high temperatures," said Richard N. Bradley, M.D., associate professor of emergency medicine and chief of EMS and disaster medicine at The University of Texas Medical School at Houston.
Congressional leaders and leading pharmaceutical companies have come up with a plan to reduce medication costs for millions of senior citizens enrolled in the Medicare Part D Prescription Drug program. In combination with other discount programs and rebates, the savings to the U.S. government could represent $80 billion. The Pharmaceutical Research and Manufacturers of America (PhRMA) is leading the charge to specifically close the coverage gap for patients whose medications costs fall into the "doughnut hole."
Carl Zeiss has developed a unique series of solutions addressing the different methods for brain mapping and soft tissue imaging. "Scientists are right now attacking one of the last secrets of mankind: imaging and reconstruction of the brain," Dr. Dirk Stenkamp, Member of the Board at Carl Zeiss SMT explains. "We specifically enable the acquisition and analysis of cell images at ultra-high resolution. For that purpose we have developed an extensive range of solutions, based on the sophisticated use of advanced electron and ion-beam microscopes," Stenkamp adds.
Acucela, a clinical-stage biotechnology company focused on developing new treatments for blinding eye diseases, announced today that data on the company"s novel visual cycle modulator, ACU-4429, a potential oral treatment for dry age-related macular degeneration (AMD), will be featured at the Aegean Retina XI Meeting being held in Crete, Greece from July 3 to 5, 2009. Dry AMD is a leading cause of vision loss in people over the age of 50, yet there are no therapies currently approved to treat this condition.
An entomology professor at the University of California, Davis who discovered a novel therapeutic target for treating inflammation, has received a three-year $750,000 grant from the American Asthma Foundation to investigate whether his discovery will work on asthma, a chronic disease affecting 300 million people worldwide, including 23 million Americans.
Latest Erbitux® (cetuximab) data presented today at the World Congress on Gastrointestinal Cancer (WCGIC) reinforce the value of the targeted therapy in the treatment of metastatic colorectal cancer (mCRC) patients with KRAS wild-type (wt) tumors. Results from the CRYSTALa and CELIMb trials have provided further evidence that KRAS mutation status is the current accepted standard predictive biomarker for Erbitux efficacy in patients with mCRC. In addition, new data have shown that the rash associated with Erbitux therapy can be effectively treated with a cream containing vitamin K.
Men are twice as likely as women to not protect their skin in the sun, despite more men dying from melanoma than women, according to research due to be released at the British Association of Dermatologists annual conference in Glasgow next month.
IRIN Examines Hardships Facing Parents, Guardians Of Children Living With HIV/AIDS
Local campaigners met with MPs and senior primary care trust staff at a parliamentary event today to raise awareness of HIV and discuss ways to increase HIV testing.
The journal Lancet Infectious Diseases examines the worldwide spread of extensively drug-resistant tuberculosis (XDR-TB). Currently, about 500,000 of the 9 million new cases of TB that are identified each year are strains of XDR-TB. "Drug resistance is largely man-made - it is vitally important to review antibiotic treatment strategies and to ensure the Stop TB Strategy is fully applied to prevent further selection of drug-resistant mutants," Leonard Amaral of Universidade Nova de Lisboa said.
Oprah Winfrey "has scored good ratings with her health episodes" of her television show, but "in doing so, she seems to have thrown therapeutic caution to the wind," such as on her shows featuring actress Suzanne Somers" opinions on bioidentical hormone replacement therapy, Salon contributor and physician Rahul Parikh writes in an opinion piece. Somers, while advocating for the use of bioidentical HRT as a safe alternative to traditional HRT for postmenopausal women, said she used "mega-doses of bioidenticals continuously and aggressively," according to Parikh. Parikh writes that Somers, on television and in her 2007 book, "argues that these hormones are more natural, more effective and safer than what doctors prescribe." According to Parikh, "In reality, ...÷ there are no good medical studies to back up those claims."Parikh says that although "what Somers was advocating was radically different from standards of medical care," Winfrey "was not concerned" and even said that Somers ""might be a pioneer,"" Parikh continues. Winfrey billed the episode as part of a ""great debate"" on hormone therapy, but she "didn"t ask about whether [Somers"] super-hormone regimen could have contributed to Somers" history of breast cancer"; "her hysterectomy, the result of pre-cancerous changes in her uterus from her use of HRT"; or the "validity of Somers" book"s s, many of whom are neither experts in women"s health or endocrinology, nor board-certified physicians, nor experienced researchers," Parikh states. He adds, "It"s not that Winfrey doesn"t try to maintain medical credibility in her shows," but "her efforts seem subpar," noting that her show "reaches millions of people, while each doctor can reach only one patient at a time." Parikh concludes, "That could easily be corrected by Winfrey providing more thought and balance in her medical advice" (Parikh, Salon, 5/15).
Researchers at the Duke University Institute for Genome Sciences & Policy have found that variation in the same gene in humans and baboons produces the same kind of disease resistance. The findings were published in the June 24 online edition of the journal Nature.
In his weekly radio and Internet address, President Obama discussed efforts by congressional leaders and health care industry groups on health care reform legislation, The Hill reports. He said that "while there remains a great deal of difficult work ahead, I am heartened by what we have seen these past few days: a willingness of those with different points of view and disparate interests to come together around common goals -- to embrace a shared sense of responsibility and make historic progress" (Youngman, The Hill, 5/16). He said, "I have always believed that it is better to talk than not to talk, that it is far more productive to reach over a divide than to shake your fist across it," which has "been an alien notion in Washington for far too long, but we are seeing that the ways of Washington are beginning to change."In the Republican radio and Internet address. Rep. Charles Boustany (R-La.), a cardiovascular surgeon, said that a "government takeover of health care will put bureaucrats in charge of health care decisions that should be made by families and doctors." He added, "It will limit treatment options and lead to rationed care," and "to pay for government health care, your taxes will be raised." Boustany, a member of the House Republican Health Care Solutions Group, said, "That is something we cannot support, and frankly, it would clearly violate some of the principles the president himself has endorsed" (Superville, AP/Washington Post, 5/16). In related news, Office of Management and Budget Director Peter Orszag on Sunday said on CNN"s "State of the Union" that the administration might support taxing health care benefits to health pay for health care reform (Barr, Politico, 5/17). Timeline
The National Cancer Intelligence Network (NCIN) and Cancer Research UK has today (Thursday) published the first report on cancer incidence and ethnicity.
A thorough cost-benefit analysis that includes an assessment of meaningful alternatives is needed to reveal the potential security advantages of deploying new detector systems to screen cargo for nuclear and radiological materials at U.S. ports and border crossings. It is likely that the costs will exceed the savings gained from improved efficiency of the screening systems, says a new report from the National Research Council. There are shortcomings in the U.S. Department of Homeland Security"s testing of these new detector systems, therefore the DHS secretary cannot conclude whether they will consistently outperform the current ones. DHS should not proceed with further procurement of these new detector systems until the issues are addressed and the systems have been shown to be a favored option in the cost-benefit analysis.
Diabetes UK supporters Harrison Ward, 11, and Cole Barnard, 6, appeared on BBC 1"s The One Show this week to highlight inequalities in support for children with diabetes at school.
Apthera, Inc. announced that it reached an agreement with the U.S. Food and Drug Administration (FDA) under a Special Protocol Assessment (SPA) for its planned Phase III clinical trial of the Company"s lead drug, NeuVax. The SPA is a written agreement between the trial"s sponsor and the FDA regarding the design, endpoints, and planned statistical analysis of the Phase III trial to be used in support of a Biologics License Application (BLA).
The Washington Post on Saturday examined the role of the Healthcare Information and Management Systems Society in lobbying for the national adoption of health information technology as part of health reform efforts. According to the Post, HIMSS has collaborated with various allies, including technology vendors and research groups, "in a sophisticated, decade-long campaign to shape public opinion and win over Washington"s political machinery."HIMSS in the early part of this decade forged a "strategic alliance" with the Center for Information Technology Leadership, a not-for-profit health IT research group in Massachusetts, to develop and distribute data reports on the cost efficiency and benefits of health IT, the Post reports. CITL also had sponsorship ties with several health and technology companies, including Google, Microsoft, Kaiser Permanente and Siemens Medical Solutions. In 2004, CITL issued a report that concluded in part that a national health IT system could reduce spending by as much as $77.8 billion by limiting drug prescribing errors and notifying providers of more cost-effective drug alternatives.According to the Post, the findings of the report were used by the Obama administration in developing the $787 billion federal economic stimulus package, which included billions in new spending for the creation and adoption of health IT systems. Although a Congressional Budget Office report found that the assumptions of CITL report were "overly optimistic" -- a follow-up CBO analysis projected that electronic health records would reduce health care spending by $17 billion over 10 years -- the health IT measures in the stimulus package "represented a triumph" for HIMSS, "whose members now stand to gain billions in taxpayer dollars," the Post reports. The Post notes that HIMSS" "sudden success shows how the economic crisis created a remarkable opening for a political and financial windfall: the enactment of a sweeping new policy with no bureaucratic delays and virtually no public debate about an initiative aimed at transforming a sector that accounts for more than a sixth of the American economy" (O"Harrow, Washington Post, 5/16).Please note: The Kaiser Family Foundation is not associated with Kaiser Permanente or Kaiser Industries.
Dr. Arne Ostman and colleagues at the Karolinska Institutet in Stockholm have identified a stromal marker for breast cancer progression. They present these findings in the July 2009 issue of the American Journal of Pathology.
A group led by Dr. Alberto Bardelli at The University of Turin Medical School reports that myoglobin may protect against the stresses of tumor growth. This study can be found in the July 2009 issue of the American Journal of Pathology.
South London Healthcare NHS Trust (SLHT) is delighted to announce a new partnership with the NHS Institute for Innovation and Improvement as part of the trust"s drive for
Frankenman International Ltd, the manufacturer and supplier of surgical instruments, announced that its entire CHEX™ range of surgical staplers had been granted FDA approval. This development complements the CE and ISO accreditation it has already acquired. FDA approval endorses Frankenman"s commitment to total quality in surgical stapling and wound closure devices, and further validates its position as a trusted alternative supplier in these markets.
US and UK scientists are developing a test for prostate cancer that uses samples of prostate fluid taken through a needle inserted under local
Higher selenium levels in the blood may worsen prostate cancer in some men who already have the disease, according to a study by researchers at Dana-Farber Cancer Institute and the University of California, San Francisco.
Retinoic acid, a derivative of vitamin A, could lead researchers to a new set of drug targets for treating breast cancer, researchers from the University of Chicago report in the June 25, 2009, issue of the journal Cell.
A new study by scientists in California concluded that exposure to local traffic-generated air pollution is linked to an increased