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Timing Is Everything: Growth Factor Keeps Brain Development On Track
Just like a conductor cueing musicians in an orchestra, Fgf10, a member of the fibroblast growth factor (Ffg) family of morphogens, lets brain stem cells know that the moment to get to work has arrived, ensuring that they hit their first developmental milestone on time, report scientists at the Salk Institute for Biological Studies in the July 16, 2009, edition of the journal Neuron.
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Pediatric Carbon Monoxide Poisoning Linked To Video Games After Hurricane Ike
Hours after Hurricane Ike roared ashore in Texas, more than two million homes were without power, which left some scrambling to preserve food and others looking for ways to entertain children, a move that proved to be, in some instances, poisonous. Researchers at The University of Texas Health Science Center at Houston found that 75 percent of children treated for carbon monoxide poisoning caused by gasoline-powered electrical generators were playing video games
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Discovery Of Genetic Links To Age Of First Menstrual Period And Menopause
Newly identified gene variants associated with the age at which females experience their first menstrual period and the onset of menopause may help shed light on the prevention of breast and endometrial cancer, osteoporosis, and cardiovascular disease.
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Varying Reductions In Breast Cancer Suggest Hormone Therapy To Blame

The recent decline in invasive breast cancer in the US was significantly less pronounced in the poor and those who live in rural areas. Researchers writing in the open access journal BMC Medicine suggest this may be due to varying reductions in the numbers of women taking hormone therapy (HT). Christina Clarke, Ph.D., led a team of researchers from the Northern California Cancer Center who studied breast cancer incidence data from the largest cancer database available in the US for the years 1997-2004, comparing poor areas against rich and urban areas against rural. She said, "Between 2001 and 2004, incidence rates of invasive breast cancer declined more than 8% in the United States. "One possible explanation for this is widespread discontinuation of and/or failure to initiate HT. Because this cessation of HT use was more pronounced in rich/urban areas, we wanted to see if there was a corresponding difference in breast cancer incidence between these areas and poor/rural parts of the country". The researchers found that overall invasive breast cancer incidence fell 13.2%, with greater reductions among women living in urban (-13.8%) versus rural (-7.5%) and low- (-13.0%) or middle- (-13.8%) versus high- (-9.6%) poverty counties. Breast cancer incidence trends for rural counties, which peaked in 1999 and then declined steadily, differed from those observed in urban counties, where rates fell dramatically after 2002. The researchers speculate that this may be due to variations in exposure to the news that HT was associated with breast cancer, they cite a 2007 report that found that the number of newspaper articles about the harmful effects of HT found in the 2002 Women"s Health Initiative (WHI) trial correlated with urban residence and likelihood of HT cessation/non-initiation; women in urban areas were potentially exposed to more newspaper articles and had a larger decline in the prevalence of HT use. Dr. Clarke added that "Understanding what specific populations were involved in the breast cancer declines helps us to better plan prevention efforts for the future, especially with the aging of the baby boomer population into prime breast cancer age." Recent trends in breast cancer incidence in US white women by urban/rural and poverty status Amelia K Hausauer, Theresa HM Keegan, Ellen T Chang, Sally L Glaser, Holly Howe and Christina A Clarke BMC Medicine (in press) Article. All articles are available free of charge, according to BioMed Central"s open access policy. Graeme Baldwin BioMed Central


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