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Spike In Severe Weather And Looming Alzheimer's Disease Epidemic - A Formula For Disaster
As the 2009 hurricane season begins, the MIT AgeLab and the Advance 50 Team of gerontologists at The Hartford Financial Services Group, Inc., offer new research and life-saving tips to help caregivers, family and friends of those with Alzheimer"s disease who live at home prepare for a natural disaster and get their lives back on track in the aftermath.
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UK Reports First Swine Flu Death
The UK reported its first death to H1N1 swine flu on Sunday after a 38-year old mother from Glasgow died in a Scottish hospital days after she
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House To Consider Amendment To HHS Bill To Limit Funding To Planned Parenthood Clinics
The House on Friday is expected to pass its fiscal year 2010 Labor-HHS-Education spending bill (HB 3293) after considering several Republican amendments addressing the bill"s price tag and certain policy priorities, CQ Today reports. The bill would appropriate $730.5 billion, making it the largest of the 12 annual appropriations bills. A vote is expected on a GOP amendment, offered by Rep. Mike Pence (R-Ind.), to prohibit family planning funding through the Title X program to Planned Parenthood clinics. Other expected amendments will seek to ban NIH from funding grants to research the HIV/AIDS risks associated with alcohol and substance abuse among sex workers in Asia and to strip language that would lift the ban on federal funding for needle exchange programs (Wolfe, CQ Today, 7/23).In related news, Senate Majority Leader Harry Reid (D-Nev.) on Thursday said the Senate would not vote on a health care reform bill until after Congress returns from its August recess, the New York Times reports (Herszenhorn/Zeleny, New York Times, 7/24).
Mental Health

Stromal Marker For Breast Cancer Progression Identified

Dr. Arne Ostman and colleagues at the Karolinska Institutet in Stockholm have identified a stromal marker for breast cancer progression. They present these findings in the July 2009 issue of the American Journal of Pathology. Platelet-derived growth factor (PDGF) receptors are involved in multiple stages of cancer cell growth. However, the contribution of PDGFR expression in the stroma, or surrounding supportive tissue, of the tumor remains unclear. Paulsson et al therefore characterized PDGFR expression in stroma of various tumors, including lymphoma and colon, ovarian, prostate, lung, and breast cancer. They found highly variable PDGFR expression in solid tumors, with colon and prostate tumors expressing the highest stromal levels of one type of PDGFR, PDGFí²R. In breast cancer, stromal PDGFí²R expression in pre-menopausal breast cancer patients significantly correlated with negative prognosis. These data highlight the importance of examining stromal as well as malignant cell expression of PDGF receptors in disease prognosis. Paulsson et al suggest that "the findings in the present study of robust staining procedures for PDGF receptors should motivate continued studies of the response-predicative value of stromal PDGF receptor status." Paulsson J, Sjö¶blom T, Micke P, Pontö©n F, Landberg G, Heldin C-H, Bergh J, Brennan DJ, Jirströ¶m K, ö-stman A: Prognostic significance of stromal PDGF í²-receptor expression in human breast cancer. Am J Pathol 2009, 174: 2752-2764 Angela Colmone American Journal of Pathology


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