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First Choice Of Renal Function Tests In Hepatectomy Patients

Although creatinine clearance (Ccr) has been measured clinically by a simple method as a preoperative renal function test, Ccr is not strictly equal to glomerular filtration rate (GFR). Recently, an equation for estimated GFR (eGFR) for Japanese individuals has been postulated, and eGFR has been accepted as equal to measured GFR in chronic kidney disease. However, there have been no previous studies regarding the reliability of eGFR as a preoperative renal function test. A research article published on May 14, 2009 in the World Journal of Gastroenterology addresses this problem. The research team led by Dr. Tokihiko Sawada from Dokkyo Medical University, Japan retrospectively calculated the preoperative three-variable and five-variable equations for eGFR, and compared the results with Ccr in patients undergoing hepatectomy. One hundred and ninety seven patients undergoing hepatectomy between August 2006 and August 2008 were enrolled in this study. Preoperative Ccr, a three-variable equation for eGFR (eGFR3) and a five-variable equation for eGFR (eGFR5) were calculated. Abnormal values were defined as Ccr World J Gastroenterol 2009; 15(18): 2252-2257 http://www.wjgnet.com/1007-9327/15/2252.asp Correspondence to: Tokihiko Sawada, MD, PhD, Department of Gastroenterological Surgery, Dokkyo Medical University, 880 Kitakobayashi, Mibu, Tochigi, 321-0293, Japan. Lai-Fu Li World Journal of Gastroenterology


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