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Stromal Marker For Breast Cancer Progression Identified
Dr. Arne Ostman and colleagues at the Karolinska Institutet in Stockholm have identified a stromal marker for breast cancer progression. They present these findings in the July 2009 issue of the American Journal of Pathology.
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Trius Announces Positive Results From Phase 2 Clinical Trial Of Torezolid In Patients With Complicated Skin And Skin Structure Infections
Trius Therapeutics, Inc. announced results from its Phase 2 clinical trial evaluating the safety and efficacy of oral torezolid (TR-701), its investigational antibiotic for the treatment of severe complicated skin and skin structure infections (cSSSI) caused by gram-positive bacteria, especially drug-resistant strains such as methicillin-resistant Staphylococcus aureus (MRSA). The study achieved its primary goals of establishing safety and efficacy in all doses evaluated.
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Miami-Dade County, Fla., Launches Campaign Promoting Routine HIV Testing
The Miami-Dade County Department of Health on Thursday launched a campaign called "Test Miami,"" which is designed to educate physicians, at-risk communities and pregnant women on the importance of routine HIV testing, the Miami Herald reports. ""A major emphasis of the campaign is to train and educate physicians, particularly in hospitals and other medical facilities,"" Evelyn Ullah, director of the Office of HIV and AIDS in Miami, said. As part of the campaign, over the next year, four area physicians will appear in advertisements and speak at forums to encourage medical providers to offer routine HIV testing. Florida is one of the states hardest hit by HIV/AIDS (Montes-Delgado, Miami Herald, 6/26). Separately, nonprofit groups and public health departments in Southwest Florida are offering free HIV testing as part of National HIV Testing Day (Freeman, Naples Daily News, 6/25).
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FDA Requests Labeling Change For Leukotriene Modifiers

The U.S. Food and Drug Administration provided further updated safety information on a class of asthma drugs known as leukotriene modifiers. The FDA has requested that manufacturers include a precaution in the drug prescribing information (drug labeling) regarding neuropsychiatric events (behavior, mood changes) that have been reported in some persons taking montelukast (Singulair), zafirlukast (Accolate), and zileuton (Zyflo and Zyflo CR). Leukotrienes are chemicals the body releases in response to an inflammatory stimulus, such as when a person breathes in an allergen. Montelukast and zafirlukast are leukotriene receptor antagonists that work by blocking leukotrienes. Zileuton is a leukotriene synthesis inhibitor which works by stopping the formation of certain substances that cause swelling, tightening, and mucus production in the airways. U.S. Food and Drug Administration


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