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First Viable Treatment Option For Highly Resistant Form Of CML May Be Provided By ChemGenex's Omacetaxine
ChemGenex Pharmaceuticals Limited (ChemGenex) (ASX:CXS) announced that the latest data from its pivotal study of omacetaxine in patients with T315I-positive chronic myeloid leukemia (CML) was the subject of an oral presentation and discussion at the 2009 American Society of Clinical Oncology (ASCO) Annual Meeting in Orlando, Florida. The open label Phase 2/3 study (CGX-635-CML-202) investigated the use of omacetaxine, administered subcutaneously in CML patients who had failed imatinib and who have the highly drug resistant T315I kinase domain mutation.
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No Shriners Hospitals Closing; Some May Be Outpatient-Only
"All 22 Shriners Hospitals for Children will stay open, but some eventually might become outpatient-only surgery facilities, the system that offers free specialty pediatric care said Thursday," CNN reports. "The system, which has covered all costs of its patients" care throughout its 87-year history, eventually will accept insurance from patients who have it, members of the Shriners fraternity decided in their annual convention in San Antonio, Texas. Accepting money from insurers and finding other ways to cut costs will help Shriners retain their presence in all 22 locations, said Doug Maxwell, the new president and CEO of Shriners Hospitals."
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Culturally Appropriate Nutritional Intervention Needed, According To Nutrition Experts
The prevalence of overweight in the US population is among the highest in Mexican-American children and adolescents. In a study of 1,030 Hispanic children between the ages of 4 and 19, published in the June 2009 issue of the Journal of the American Dietetic Association, researchers from the Baylor College of Medicine found less than optimal diets in both overweight and non-overweight participants.
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Diabetes: Long And Short Sleep Durations Are Associated With Increased Risk

According to a research abstract presented on Monday, June 8, at SLEEP 2009, the 23rd Annual Meeting of the Associated Professional Sleep Societies, both long and short sleepers are at greater risk for diabetes. Individuals sleeping for more than eight hours per night may be particularly vulnerable. Results indicate that the adjusted odds ratio was 1.24 for diabetes associated with short sleep (five hours per night or less) and 1.48 for diabetes associated with long sleep (nine or more hours per night). The prevalence of diabetes was 12 percent for blacks and 8 percent for whites, and the prevalence of obesity (body mass index of 30 kg/m2 or greater) was 52 percent for blacks and 38 percent for whites. According to lead author Girardin Jean-Louis, PhD, associate professor at the SUNY Downstate Medical Center at the Brooklyn Health Disparities Research Center in New York, findings suggest that both patients who have excessive or insufficient sleep time have increased risk for developing diabetes, a serious health condition. "Both blacks and whites who were obese tended to have short sleep time. These findings suggest that race significantly influenced the risk of obesity conferred by short sleep duration," said Jean-Louis. "As obesity is associated with diabetes and sleep apnea, it may be that more blacks are at risk for sleep apnea and diabetes, which are both linked to cardiovascular disease." The study involved data from 29,818 individuals who completed the 2005 National Health Interview Survey, a cross-sectional household interview survey using multistage area probability and design. Data were collected from all 50 states and Washington, D.C. Participants were between the ages of 18 and 85 years; 85 percent of the sample was white and 15 percent was black; 56 percent of participants were women. The authors conclude that more research is needed to identify the factors that could explain the relationship between long sleep duration and diabetes. Abstract Title: Sleep duration and risk of diabetes: analysis of the National Health Interview Survey Presentation Date: Monday, June 8 Category: Sleep Deprivation Abstract ID: 0459 Kelly Wagner American Academy of Sleep Medicine


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